Not a steroid hormone but a beta-2-symphatomimetic,
clenbuterol also has a strong anti-catabolic effect which inhibits the rate at which protein is reduced in the
muscle cell causing cell enlargement. It is a beta-2 adrenergic agonist that causes an increase in aerobic capacity, an increase in blood pressure and oxygen transportation and greater CNS (central nervous system) stimulation.
clenbuterol also increases the manufacture and secretion of cathecholamines (catabolic hormones) such as epinephrine, norepinephrine and dopamine. This in turn increases aerobic capacity and in conjunction with the heightened state of the CNS leads to greater stimulation of the skeletal
muscle system. Secreted from the adrenal region, catabolic hormones have many functions; not least of these is their ability to very specifically alter the contractile character of smooth
muscle. Some will be inhibited whilst others will be stimulated. For example the smooth
muscles of the bronchial tree will be inhibited. This is said to have a soothing effect in patients with breathing difficulties and as such is administered as a decongestant and bronchodilator.
Clenbuterol will also inhibit and reverse the effects of insulin resulting in a release of glycogen into the circulatory system. It also impairs the ability to store or use more glycogen and increases the rate at which protein and
fat (adipose tissue) are consumed due to the increased metabolic functions of the subject.
Clenbuterol is very efficient at
burning
fat as it slightly increases body temperature. This increase in temperature forces the body to
burn fat for this process. A rise of 1.0Û« F in body temperature can result in a 5% reduction of adipose tissue (
fat). Due to this ability to
burn fat without
dieting it is now a popular, if illegal, drug with
slimmers. If used in conjunction with a sensible
diet and cardiovascular
exercise it produces very good results.Body builders also appreciate the higher metabolic rate as it
burns more calories, essential for a leaner, tighter physique with cuts and striations. Be aware also of the fact that whilst
fat is taken from adipose tissue most protein
loss will occur in
muscle tissue. As with all catabolic hormones
muscle loss is inevitable. With this in mind it is often used for a 3 week period during a cycle of anabolic steroids that will preserve the lean
muscle mass whilst still removing
fat.Because aerobic capacity and oxygen transportation are also increased,
clenbuterol is also very attractive to athletes involved in endurance sports where a boost is required. Also popular with distance runners and a firm favourite of cyclists in it`s liquid form.
Tests conducted on animals revealed that
clenbuterol also acted as an anabolic capable of imparting
muscle gain. As the opposite would appear to be the case in humans it must be pointed out that the animals were fed
dosages considerably higher than would be tolerated by humans. Also under fierce discussion is the possibility of a "beta-3" receptor not found in humans. Dosages taken by people are measured in micrograms with the
dosage building to a maximum daily intake before reducing once again to the original daily dose. A period of 3 weeks on 3 weeks off would appear to be very popular as
clenbuterol becomes less effective as the body becomes more tolerant. Body homeostasis will attempt to negate the functions of
clenbuterol. The off period ensures that the body remains receptive to the effects and bene
fits you wish to achieve. A typical 21 day regime may be as follows: 40/40/40/60/60/60/80/80/80/100/100/100/80/80/80/60/60/60/40/40/40 mcg daily followed by 21 days rest. Dosages should not exceed 160 mcg for men 120 mcg for
women. One should also decrease the dose if the side effects make it necessary.
Side effects can include:
Headaches
Muscular tremors (especially hand shakes)
Muscular cramps
Nervousness
Insomnia
Sweating
Increased appetite
Nausea
Palpitations
Hypertension (high blood pressure)
Possible cardiac hypertrophy as
clenbuterol also targets cardiac and smooth
muscle fibres
Heart
muscle necrosis has been demonstrated in animal studies
Given the added pressures put on the body due to increased metabolic rate, body temperature etc it is not recommended that people with heart conditions and or high blood pressure use any performance related products without prior medical consultation. Also be aware that there are possible liver toxicity issues if
clenbuterol is "stacked" with accutane, anti-biotics, 17-alpha-alkylated steroids, or other hepatoxic elements.
